What is osteonecrosis of the jaw?

In some patients who have taken bisphosphonates and denosumab (osteoporosis medication), a condition known as osteonecrosis of the jaw (also called ONJ) has been reported. Osteonecrosis of the jaw is a rare but serious condition that can cause severe damage to the jawbone. Osteonecrosis of the jaw is diagnosed in a patient who:

1. has an area of exposed bone in the jaw that lasts for more than 8 weeks
2. has no history of radiation therapy to the head and neck
3. is taking, or has taken, certain osteoporosis medicines

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Important: This content reflects information from various individuals and organizations and may offer alternative or opposing points of view. It should not be used for medical advice, diagnosis or treatment. As always, you should consult with your healthcare provider about your specific health needs.