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Who should not use oxymetazoline?

You must not use over-the-counter oxymetazoline nasal sprays if you have taken a monoamine oxidase inhibitor (MAOI) within the past 14 days, due to a potentially dangerous interaction. These include isocarboxazid (Marplan), phenelzine (Nardil), selegiline (Eldepryl, Emsam, Zelapar), and tranylcypromine (Parnate).
Children under six years of age should not use oxymetazoline nasal sprays, unless a doctor recommends it. Also, inform your doctor before using these nasal sprays if you are pregnant, breastfeeding, allergic to oxymetazoline or other drugs or have any of the following conditions:
  • glaucoma or pressure in the eye
  • high blood pressure
  • hardening of the arteries
  • heart disease
  • erratic heartbeat
  • diabetes
  • kidney or liver disease
  • enlarged prostate or trouble urinating
  • thyroid problems

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Important: This content reflects information from various individuals and organizations and may offer alternative or opposing points of view. It should not be used for medical advice, diagnosis or treatment. As always, you should consult with your healthcare provider about your specific health needs.