What should I know before receiving ranibizumab?

Before starting ranibizumab (brand name Lucentis) injections, which is used for the eye condition called macular degeneration, among other things, you should know the following:
  • Getting injections into the eye (called intravitreal injections) could cause inflammation and infection within the eyeball, called endophthalmitis. It could also cause retinal detachment, which is when the retina tears away from the eyeball.
  • The pressure within your eyeball may go up after getting an injection with a drug like ranibizumab. If this happens, it usually occurs within the first hour after the injection.
  • You may find that your vision is abnormal for a time after your ranibizumab injection. Until these visual disturbances have gone away, you should not drive or use machinery.
  • Ranibizumab and other drugs in its category (VEGF-A antagonists) can put you at a higher risk for strokes and other problems caused by blood clots.
  • If you are thinking about using this drug as a long-term treatment for your age-related macular degeneration, you should know that scientists don't know if it's safe and effective to use it for longer than two years.

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Important: This content reflects information from various individuals and organizations and may offer alternative or opposing points of view. It should not be used for medical advice, diagnosis or treatment. As always, you should consult with your healthcare provider about your specific health needs.