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How is pegaptanib (Macugen) given?

Pegaptanib (Macugen) treats neovascular age-related macular degeneration (wet macular degeneration) a leading cause of irreversible vision loss where the blood vessels leak into the macula of the eye. Pegaptanib is a vascular endothelial growth factor (VEGF) antagonist that works by blocking abnormal blood vessel growth. It is injected into the eye by an ophthalmologist once every six weeks. Before the medicine is injected, your eye will be cleaned with a sterile solution and a numbing agent will be placed in the eye so you will only feel a little discomfort from the pressure but no pain.

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