When can I stop taking Nucynta ER?

You can stop taking the pain medication Nucynta ER (extended release tapentadol) when you no longer need it to control pain, but you should only do this with your doctor's supervision. It's possible for your body to become dependent on the medication. If you stop taking it suddenly, you could experience serious withdrawal symptoms, including anxiety, sweating, nausea and vomiting. Unless it's an emergency, your doctor will likely lower your dose slowly over time so that you avoid withdrawal problems.