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What are possible side effects of Subutex?

The side effects of Subutex (buprenorphine) can range from manageable and temporary to life-threatening. Subutex is prescribed to adults to treat addiction to opioid drugs, including heroin and narcotic painkillers like morphine. Call your doctor if any of the following common side effects from taking Subutex are severe or persistent:

- headache
- nausea
- vomiting
- excessive sweating
- constipation
- difficulty falling or staying asleep
- pain
- drug withdrawal syndrome (including drug craving, shaking, chills alternating with flushing, runny nose, watery eyes, cramps, muscle aches, vomiting, diarrhea, goose bumps)

You or someone with you should call the doctor or 911 immediately if you experience any of the following potentially serious side effects while taking Subutex:
  • dizziness
  • extreme tiredness
  • fainting 
  • confusion or foggy thinking
  • slowed breathing or breathing difficulty
  • feeling sleepy and uncoordinated, slow reflexes
  • blurred vision
  • slurred speech
  • lack of energy
  • yellowing of your skin or the whites of your eyes
  • pain in the upper right part of the stomach
  • unusual bleeding or bruising
  • dark urine
  • light-colored stools
  • loss of appetite
  • flu-like symptoms
  • signs of allergic reaction (rash, hives, facial swelling, wheezing, itching, trouble swallowing)
  • loss of consciousness

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Important: This content reflects information from various individuals and organizations and may offer alternative or opposing points of view. It should not be used for medical advice, diagnosis or treatment. As always, you should consult with your healthcare provider about your specific health needs.