What is the origin of methadone?

Methadone is a synthetic opioid. Discovered by the Germans in World War II and called dolophine, it lasted much longer than morphine and was used to rid the wounded of their pain. In 1947, the Eli-Lilly company purchased it and named it methadone. In 1964, it started being used to stabilize people detoxifying from heroin. In 1970, the U.S. Food and Drug Administration (FDA) regulated methadone as a treatment for opioid addiction. In 2001, the Drug Enforcement Administration (DEA) took over the role of regulating methadone as a treatment method. In 2005, both methadone and buprenorphine were named on a model list of essential medicines by the World Health Organization (WHO).

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