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What medications can cause breathing problems when taken with opioids?

Travis M. Hendry, MD
Orthopedic Surgery
Medications that interact with opioids to decrease breathing include clonazepam (Klonopin), alprazolam (Xanax), lorazepam (Ativan), zolpidem (Ambien), antihistamines (such as Benadryl), anti-nausea medications (such as promethazine/Phenergan), and muscle relaxants (such as carisoprodol/Soma).

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