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What other drugs affect Opana ER?

Before taking Opana ER, give your doctor a list of all the prescription or non-prescription medications, supplements, vitamins or herbs you take.

Opana ER might negatively interact with certain medications, including other narcotic medications; any medication that can slow your breathing or make you drowsy or sleepy, including sedatives, sleeping pills, muscle relaxers and tranquilizers; medications used to treat mental illness, depression and anxiety; medications used to treat Parkinson's disease, including benztropine and trihexyphenidyl; medications used to treat motion sickness, including scopolamine; medications used to treat bladder disorders, including oxybutynin and tolterodine; and medications used to treat stomach disorders, including dicyclomine and hyoscyamine.

Opana ER may also interact with antihistamines, atropine, benzodiazepines, buprenorphine, butorphanol, ipratropium, nalbuphine, naltrexone, pentazocine, phenothiazines (including chloropromazine, thioridazine, mesoridazine and prochlorperazine), and tramadol.

Don't consume any alcohol, including foods or medications that contain alcohol, while taking Opana ER, as the combination can lead to serious, potentially fatal side effects.

Opana ER is not likely to interact with specific foods, but you should take it on an empty stomach at least one hour before or two hours after a meal.

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Important: This content reflects information from various individuals and organizations and may offer alternative or opposing points of view. It should not be used for medical advice, diagnosis or treatment. As always, you should consult with your healthcare provider about your specific health needs.