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What are the possible side effects of Opana ER?

Seek emergency medical treatment if you experience serious side effects while taking Opana ER, including rapid, slow or irregular heartbeat; shallow, slow or difficult breathing; a severe headache; confusion; unusual thoughts, including hallucinations; mood changes; seizures; unusual or extreme drowsiness; severe dizziness or lightheadedness; fainting; unusual or extreme weakness.

See a doctor immediately if you have vision changes; dry eyes, including discomfort when wearing contact lenses; severe vomiting; unusual swelling; clammy, cold skin; red, peeling, blistering or loose skin, including inside your mouth; fever; and decreased ability to urinate.

Seek immediate medical care or call 911 if you experience symptoms of an allergic reaction, including breathing difficulty, tightness in your chest, hives, a rash, itching or swelling in your face, lips, tongue or throat.

More common, less dangerous side effects, include: mild headaches, decreased appetite, nausea, vomiting, constipation, gas, mild dizziness or lightheadedness, mild drowsiness, itching, sweating, dry mouth and anxiety. Talk to your doctor if any of these side effects is severe or persistent.

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Important: This content reflects information from various individuals and organizations and may offer alternative or opposing points of view. It should not be used for medical advice, diagnosis or treatment. As always, you should consult with your healthcare provider about your specific health needs.