What are the side effects of nalmefene hydrochloride?

You may have an allergic reaction to nalmefene hydrochloride requiring emergency medical attention. Symptoms of an allergic reaction include itching, hives, or skin rash; difficulty breathing; and swelling of your face, lips, tongue, or throat. The following side effects associated with using nalmefene hydrochloride require prompt medical attention: extreme drowsiness; stomach cramps; weak or shallow breathing; chest pain or fluttering in your chest; pain that was controlled by narcotic pain medicine; high blood pressure; seizures; and feeling like you might pass out. Other side effects are generally minor and only require medical attention if they persist or disrupt your daily life. These include nausea, vomiting, diarrhea, and stomach pain; muscle or joint pain; fever, sweating, or chills; runny nose; trembling; weakness; and feeling, irritable, anxious, restless, or depressed.

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