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How does Ultram ER differ from Ultram?

Ultram ER is the extended-release and long-acting version of the prescription pain reliever Ultram (tramadol). An Ultram ER tablet provides pain relief for 24 hours, while an Ultram tablet is typically taken every four to six hours.

Ultram ER is used to manage moderate to moderately severe chronic pain in adults who need around-the-clock pain treatment for an extended period of time. It is available in doses of 100, 200 and 300 milligrams (mg). Consistency is important when taking Ultram ER. The extended-release tablets should be taken whole, once a day at about the same time of day. You can take it with or without food, but you should pick one of those options and stick to it.

Ultram is also used for moderate to moderately severe pain, but it's available only in 50 mg tablets. It can be taken at any time of day, with or without food.

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Important: This content reflects information from various individuals and organizations and may offer alternative or opposing points of view. It should not be used for medical advice, diagnosis or treatment. As always, you should consult with your healthcare provider about your specific health needs.