How does belladonna and opium interact with other medications or foods?

Stacy Wiegman, PharmD

Pharmacy

Some medications known to interact with belladonna and opium suppositories include:

cold and allergy medicines
other narcotics
antidepressants
drugs for treating mental illness
blood thinners
cimetidine
rifampin
diazepam or other similar medicines

Specifically, the effectiveness of belladonna and opium suppositories may decrease if used with nalbuphine, naltrexone, pentazocine, butorphanol and buprenorphine. In addition, belladonna and opium suppository side effects may increase if used with MAOIs, sodium oxybate or GHB, cimetidine, phenothiazines and furazolidone. Be sure to discuss all medications, supplements and recreational drug or alcohol use with your doctor before using belladonna and opium suppositories.

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Important: This content reflects information from various individuals and organizations and may offer alternative or opposing points of view. It should not be used for medical advice, diagnosis or treatment. As always, you should consult with your healthcare provider about your specific health needs.