Can I use Ultram if I have a history of breathing problems?

If you have a history of breathing problems -- such as asthma, sleep apnea or a chronic obstructive pulmonary disease (COPD) like emphysema or chronic bronchitis -- talk to your doctor before taking Ultram (tramadol), a prescription drug for moderate to moderately severe pain. Some studies suggest that Ultram may be a good pain medication option for people with pulmonary disorders because it does not release histamine, a chemical that is known to aggravate breathing problems.