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Can I use Subutex if I am taking phenobarbital?

If you are taking phenobarbital, talk to your doctor and pharmacist before taking Subutex (buprenorphine), a medicine that helps treat addiction to opioids, including heroin, morphine and other narcotic painkillers. Phenobarbital is a sedative that is prescribed to treat anxiety, seizures and other problems. Like Subutex, phenobarbital depresses your central nervous system; when these drugs are taken together, they can slow your breathing a dangerous amount, possibly resulting in death. Your doctor may tell you not to take both drugs. Alternatively, he or she may adjust the doses of the drugs and monitor you closely.

Phenobarbital is one of many drugs that may interact with Subutex. Before starting treatment with Subutex, give your doctor and pharmacist a list of all your other medicines (prescription and nonprescription) and herbal and dietary supplements. Once you're on Subutex, do not take any new drug or supplement without checking with your doctor and pharmacist first.

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Important: This content reflects information from various individuals and organizations and may offer alternative or opposing points of view. It should not be used for medical advice, diagnosis or treatment. As always, you should consult with your healthcare provider about your specific health needs.