Can I use Ryzolt if I am taking tricyclic antidepressants?

Talk to your doctor before taking the long-acting prescription pain medication Ryzolt (tramadol extended-release tablets) if you use a tricyclic antidepressant, such as:
  • amitriptyline
  • amoxapine
  • clomipramine 
  • desipramine 
  • doxepin
  • imipramine 
  • protriptyline
  • trimipramine 
  • nortriptyline
Combining Ryzolt with one of these medications may increase the risk of seizures, as well as a rare but serious condition called serotonin syndrome. If you're on a tricyclic antidepressant, your doctor may need to monitor you closely and modify your medication plan, dosage or timing.

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Important: This content reflects information from various individuals and organizations and may offer alternative or opposing points of view. It should not be used for medical advice, diagnosis or treatment. As always, you should consult with your healthcare provider about your specific health needs.