Can I use ConZip if I am taking antibiotics?

Stacy Wiegman, PharmD

Pharmacy

In general, you can take the pain medication ConZip (tramadol) if you're using an antibiotic. However, if you're taking ConZip along with the antibiotic linezolid (Zyvox), your doctor should monitor you closely because the two drugs together can put you at risk for serotonin syndrome, a rare but potentially deadly condition. Symptoms of serotonin syndrome include agitation, hallucinations, coma, rapid heartbeat, dramatic blood-pressure changes, dangerously high fever, coordination problems, twitching, nausea, vomiting and diarrhea.

In addition, the antibiotic erythromycin can interfere with your body's ability to break down ConZip so that more of each dose gets into your bloodstream and stays there longer, which increases the chances of side effects.

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Important: This content reflects information from various individuals and organizations and may offer alternative or opposing points of view. It should not be used for medical advice, diagnosis or treatment. As always, you should consult with your healthcare provider about your specific health needs.