Can I take an antihistamine if I use Fentora?

Stacy Wiegman, PharmD

Pharmacy

You should be very careful about mixing antihistamines with Fentora (fentanyl), a morphine-like drug for breakthrough cancer pain. Some antihistamines can worsen Fentora's side effects, causing dangerously slowed breathing and/or excessive sleepiness. Consult your doctor and pharmacist before taking any antihistamine, either prescription or over-the-counter, if you're using Fentora.

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Important: This content reflects information from various individuals and organizations and may offer alternative or opposing points of view. It should not be used for medical advice, diagnosis or treatment. As always, you should consult with your healthcare provider about your specific health needs.