Can I use Rybix ODT if I am taking St. John's wort?

Your doctor may instruct you to stop taking St. John's wort if he or she gives you a prescription for Rybix ODT (tramadol). Rybix ODT is sometimes prescribed for the relief of moderate to moderately severe chronic pain. St. John's wort is an herbal remedy that some people use to treat depression and other health problems. St. John's wort may interfere with the way your body processes Rybix ODT, so it's unwise to combine the two. Combining Rybix ODT and St. John's wort may increase the risk for a condition called serotonin syndrome. Serotonin syndrome can result in hallucinations, loss of muscle coordination, gastrointestinal problems and other serious complications. In extreme cases, serotonin syndrome can induce a coma or be fatal. Tell your doctor about all medications you use, both prescription and over-the-counter, before taking Rybix ODT.

Continue Learning about Opiate Agonists

What opioid medications can help treat severe headaches?
Egilius L. Spierings, MDEgilius L. Spierings, MD
If you suffer severe headaches frequently, if not daily, one strategy to consider is a long-acti...
More Answers
What medication should I avoid if I have a bowel obstruction?
Stacy Wiegman, PharmDStacy Wiegman, PharmD
Do not take the painkiller Avinza (morphine) if you have paralytic ileus, a partial or complete bowe...
More Answers
What should I avoid doing while on opioid medication for chronic pain?
Travis M. Hendry, MDTravis M. Hendry, MD
Take opioid pain medication (strong medications that affect the way your brain handles pain sign...
More Answers
How can I prevent breathing problems caused by opioid medications?
Travis M. Hendry, MDTravis M. Hendry, MD
Respiratory depression caused by opioid medications can be prevented by doing the following: Tel...
More Answers

Important: This content reflects information from various individuals and organizations and may offer alternative or opposing points of view. It should not be used for medical advice, diagnosis or treatment. As always, you should consult with your healthcare provider about your specific health needs.