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Can I use Oxecta if I am taking CYP3A4 inhibitors?

Unless it's necessary, you shouldn't use the pain medication Oxecta (oxycodone) if you're taking a drug that inhibits your body's CYP3A4 enzyme. These drugs include the antibiotic erythromycin, the antifungal agent ketoconazole (Nizoral) and protease inhibitors, such as ritonavir (Norvir), that are used to fight HIV infection. Taking these medications can interfere with the enzyme's ability to break down Oxecta so that an excess of each dose gets into your bloodstream and stays there longer, which increases the chance you'll develop side effects from the drug. If you do need to take a CYP3A4 inhibitor along with Oxecta, your doctor will carefully oversee your Oxecta usage. Make sure he or she knows if you are already taking one of these medications or are about to begin or stop taking one.

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Important: This content reflects information from various individuals and organizations and may offer alternative or opposing points of view. It should not be used for medical advice, diagnosis or treatment. As always, you should consult with your healthcare provider about your specific health needs.