Can I use Opana if I have a history of digestive diseases?

You should not take the pain medication Opana (oxymorphone) if you have paralytic ileus, a partial or complete bowel obstruction that prevents digested food from passing through the intestines. Because Opana tends to slow down muscle contractions in your digestive tract, it can worsen this condition. If your doctor wants to prescribe Opana for you, speak up about your paralytic ileus so that he or she can find another medication that will be safe and effective for you.