Can I use MS Contin if I am taking tranylcypromine?

Stacy Wiegman, PharmD

Pharmacy

Do not use the painkiller MS Contin (morphine) if you're taking the antidepressant tranylcypromine (Parnate) or have taken it (or any other monoamine oxidase inhibitor) in the last 14 days. Tranylcypromine can significantly increase MS Contin's potency and lead to serious overdose symptoms such as slow or shallow breathing, low blood pressure, seizure, shock, coma and even death. Before starting MS Contin, it's critical that you let your doctor know if you've taken tranylcypromine.

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Important: This content reflects information from various individuals and organizations and may offer alternative or opposing points of view. It should not be used for medical advice, diagnosis or treatment. As always, you should consult with your healthcare provider about your specific health needs.