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Can I use MS Contin if I am taking antidepressants?

The pain medication MS Contin (morphine) is safe to take along with some antidepressants but can cause serious and even potentially fatal side effects combined with others. Don't take MS Contin if you use, or have used in the last 14 days, a monoamine oxidase inhibitor (MAOI) such as tranylcypromine (Parnate), phenelzine (Nardil), selegiline (Emsam) or isocarboxazid (Marplan). MAOIs increase MS Contin's potency, which can cause an overdose that leads to slow or shallow breathing, low blood pressure, seizures, shock, coma and death.

Also let your doctor know if you're taking a tricyclic antidepressant because this could affect how much MS Contin he or she prescribes. Tricyclics include amitriptyline, amoxapine (Asendin), clomipramine (Anafranil), desipramine (Norpramin), doxepin (Adapin, Sinequan), imipramine (Tofranil), nortriptyline (Aventyl, Pamelor), protriptyline (Vivactil) and trimipramine (Surmontil).

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Important: This content reflects information from various individuals and organizations and may offer alternative or opposing points of view. It should not be used for medical advice, diagnosis or treatment. As always, you should consult with your healthcare provider about your specific health needs.