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Can I use Fentora if I take an antifungal medicine?

If you take certain antifungal medicines, such as fluconazole (Diflucan), itraconazole (Sporanox), and ketoconazole (Nizoral), while you're using Fentora (fentanyl), a prescription pill for breakthrough cancer pain, you'll need to be carefully monitored. Some antifungals can cause fentanyl -- the active ingredient in Fentora -- to build up in your body, increasing the risk of coma or fatal overdose. You and your doctor should watch for signs of a buildup, such as increased sleepiness or a sighing pattern of breathing (in which a deep breath is followed by a long pause), especially when your dose of Fentora is increased.

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Important: This content reflects information from various individuals and organizations and may offer alternative or opposing points of view. It should not be used for medical advice, diagnosis or treatment. As always, you should consult with your healthcare provider about your specific health needs.