Can I use Fentora if I take St. John's wort?

Doctors generally advise against using the herbal remedy St. John's wort if you take Fentora (fentanyl), a medication for breakthrough cancer pain. That's because St. John's Wort speeds up the body's excretion of Fentora, making it less effective against pain.

Talk with your doctor about stopping St. John's wort before you start taking Fentora. If you feel strongly that you want to continue using this herbal remedy, find out if your doctor is willing to work closely with you to find the right balance between the two substances so they are both effective. Once this balance is achieved, it's very important not to stop taking either without talking with your doctor first. Stopping St. John's wort while you're still on the same dose of Fentora puts you at risk for serious side effects, including a fatal overdose.

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Important: This content reflects information from various individuals and organizations and may offer alternative or opposing points of view. It should not be used for medical advice, diagnosis or treatment. As always, you should consult with your healthcare provider about your specific health needs.