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Can I use ConZip if I am taking tricyclic antidepressants?

Your doctor will be very careful about prescribing the pain medication ConZip (tramadol) if you're taking a tricyclic antidepressant such as amitriptyline (Elavil), amoxapine, clomipramine (Anafranil), desipramine (Norpramin), doxepin (Sinequan), imipramine (Tofranil), nortriptyline (Aventyl, Pamelor), protriptyline (Vivactil) or trimipramine (Surmontil). Reports show the combination of ConZip and a tricyclic can increase your risk of serious side effects, including seizures and serotonin syndrome, a rare but potentially deadly condition that can occur if levels of the brain chemical serotonin become too high.

Also, if you're taking a tricyclic to treat depression, be aware that ConZip increases the risk of suicide in people who are already experiencing suicidal thoughts or behaviors. Be sure your doctor knows about your depression and how it's being treated before you start to take ConZip.

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Important: This content reflects information from various individuals and organizations and may offer alternative or opposing points of view. It should not be used for medical advice, diagnosis or treatment. As always, you should consult with your healthcare provider about your specific health needs.