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ConZip (tramadol) may interact with the muscle relaxant cyclobenzaprine (Flexeril). One problem is that cyclobenzaprine is a tricyclic compound, which increases the risk of seizure when used with ConZip, a powerful pain medication prescribed for adults who need around-the-clock relief from moderate to moderately severe pain. Let your doctor know if you're taking cyclobenzaprine before you begin ConZip.
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