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Can I use Actiq if I am taking naloxone?

Naloxone (Narcan) may stop Actiq (fentanyl) from being effective. Actiq is a synthetic opiate lozenge used to treat breakthrough cancer pain in patients who are already taking opiate-type narcotics to control pain. Naloxone is an opiate antagonist—it stops your body from getting the benefits of Actiq. Naloxone may be used for the treatment of opiate addiction. Taking naloxone along with Actiq may cause serious side effects and make Actiq less effective in treating pain. However, it may be prescribed as a short-term method of treating adverse side effects of Actiq.

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