Can I use Actiq if I am taking medications for nausea?

If you're taking Actiq (fentanyl), a synthetic opiate lozenge used to treat breakthrough cancer pain, tell your doctor if you're also taking an antinausea drug—to help you cope with chemotherapy, for instance. Some antinausea drugs can have adverse interactions with Actiq; if you are taking one of these, your doctor can prescribe a different one. The antinausea drug aprepitant (Emend), for example, can cause levels of Actiq to build up in your system, which can be dangerous. Tell your doctor about every prescription drug, over-the-counter medication and supplement that you are taking.