Who should avoid nonsteroidal anti-inflammatory painkillers (NSAIDs)?

Over-the-counter (OTC) and prescription nonsteroidal anti-inflammatory drugs (NSAIDs) such as ibuprofen and naproxen can cause gastrointestinal bleeding, liver and kidney problems, and can increase the risk for a heart attack. People with asthma, liver or kidney disease, a personal or family history of cardiovascular disease, heart attack or stroke, lupus, and swelling in the hands, legs or feet may not be able to take NSAIDs.

Ibuprofen may interact with some medications including other types of pain killers, blood thinners, ACE inhibitors, diuretics (water pills), lithium and methotrexate. Pregnant and breastfeeding women should talk to a doctor before taking an NSAID. 

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Important: This content reflects information from various individuals and organizations and may offer alternative or opposing points of view. It should not be used for medical advice, diagnosis or treatment. As always, you should consult with your healthcare provider about your specific health needs.