What is sulindac?

Sulindac is an oral medication belonging to the class of drugs known as the non-steroidal anti-inflammatory drugs (NSAID) and is used to treat pain and other symptoms associated with various types of arthritis, including gouty arthritis, ankylosing spondylitits, as well as tendonitis and bursitis. Sulindac works by reducing the levels of prostaglandins, chemicals that are responsible for pain, fever and inflammation. Sulindac blocks the enzyme cyclooxygenase, resulting in lower concentrations of prostaglandins. As a consequence, the symptoms sulindac can reduce include pain, inflammation, stiffness, swelling and tenderness. Sulindac treats the symptoms, but cannot cure the underlying problems.