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Combunox is a prescription medication used as a short-term treatment for moderate to severe pain. It includes two different drugs, ibuprofen and oxycodone. Ibupofen is a nonsteroidal anti-inflammatory drug (NSAID) that is used for pain relief and fever reduction. Oxycodone is an opioid pain reliever. The two drugs together provide more effective pain relief than would either drug alone.
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