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Can Ibudone interact with other medications or foods?

The prescription pain medication Ibudone (hydrocodone and ibuprofen) is not known to interact with any foods, but it's important that you not drink alcohol while taking it. Ibudone can interact with a number of other medications. Examples of drugs that can interact with Ibudone, causing potentially serious problems, include the following:
  • angiotensin-converting enzyme (ACE) inhibitors (given for heart failure and certain other types of heart disease)
  • certain pain medications, known as agonist/antagonist analgesics, such as pentazocine, nalbuphine, butorphanol and buprenorphine
  • anticholinergics
  • certain antidepressants
  • aspirin
  • drugs that depress the central nervous system, such as other opioids, antihistamines, antipsychotics and anti-anxiety agents
  • diuretics (water pills)
  • lithium
  • methotrexate
  • muscle relaxants
  • warfarin
Before you start using Ibudone, tell your doctor about all your other prescription and over-the-counter medications, as well as any supplements and vitamins you take.

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Important: This content reflects information from various individuals and organizations and may offer alternative or opposing points of view. It should not be used for medical advice, diagnosis or treatment. As always, you should consult with your healthcare provider about your specific health needs.