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Who should not take hydrocodone and ibuprofen?

People who have had an allergic reaction to aspirin, nonsteroidal anti-inflammatory drugs (NSAIDs), hydrocodone or codeine should not take hydrocodone-ibuprofen. You should not take hydrocodone-ibuprofen if you have a history of severe kidney problems or if you have had or are scheduled to have heart bypass surgery. If you have had food poisoning or develop severe diarrhea due to antibiotics, you should not continue taking hydrocodone-ibuprofen. People taking gamma-hydroxybutyric acid (GHB) or monoamine oxidase (MAO) inhibitors should not take hydrocodone-ibuprofen unless it has been more than two weeks since they took the other medication. Pregnant women in their final trimester (three months) of pregnancy should not take hydrocodone-ibuprofen. Talk to your doctor if you have or are at increased risk for heart disease. 

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Important: This content reflects information from various individuals and organizations and may offer alternative or opposing points of view. It should not be used for medical advice, diagnosis or treatment. As always, you should consult with your healthcare provider about your specific health needs.