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Will nabumetone raise my risk of heart attack or stroke?

Nabumetone (Relafen) is drug that reduces inflammation and is used to relieve pain and swelling in people with osteoarthritis and rheumatoid arthritis. It belongs to a class of medications called nonsteroidal anti-inflammatory drugs (NSAIDs), selective COX-2 inhibitors. This group of NSAIDs, which includes nabumetone (but not aspirin, which is a different kind of NSAID), can raise the risk for dangerous blood clots that can lodge in the heart, causing a heart attack, or in the brain, causing a stroke. This can happen suddenly and without warning. It is more likely to happen to people who have taken NSAIDs for a long time, and are already at risk for a cardiovascular event because of a personal or family history of heart disease, heart attack, or stroke. And if you smoke, have high cholesterol, high blood pressure or diabetes, you are at higher risk. You should not take nabumetone right before or right after any heart surgery. Let your doctor and pharmacist know if any of these risk factors apply to you. If you experience any of the following symptoms while taking nabumetone, get emergency medical treatment: chest pain, shortness of breath, one-sided pain or weakness, particularly down the left arm and jaw, or slurred speech.

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Important: This content reflects information from various individuals and organizations and may offer alternative or opposing points of view. It should not be used for medical advice, diagnosis or treatment. As always, you should consult with your healthcare provider about your specific health needs.