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What should I know about hydrocodone and ibuprofen before taking it?

You should know that hydrocodone-ibuprofen can cause a variety of side effects and even physical dependence. Tell your doctor if you have a personal or family history of alcoholism, addiction, substance abuse, suicide attempts or mental problems. Your doctor should also know if you have a medical history of problems with your kidneys, lungs, bowel, stomach or liver. Also, tell your doctor if you have a history of:
  • diabetes
  • asthma
  • lupus
  • fluid buildup or retention
  • nasal polyps or other growths in the nose
  • inflammation in the mouth
  • blood disorders, including bleeding or clotting problems
  • heart problems, including high blood pressure, previous heart attack, atherosclerosis, heart failure or blood vessel problems
  • Addison's disease
  • thyroid problems
  • an enlarged prostate
  • trouble urinating
  • seizures
  • growths in the brain
  • general poor health
  • dehydration
  • low sodium levels in the blood
Tell your doctor if you have had a recent head injury or if you have had recent surgery. The chances of stomach bleeding are higher for elderly people taking hydrocodone-ibuprofen.

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Important: This content reflects information from various individuals and organizations and may offer alternative or opposing points of view. It should not be used for medical advice, diagnosis or treatment. As always, you should consult with your healthcare provider about your specific health needs.