How does Indocin IV interact with other medications?

Stacy Wiegman, PharmD

Pharmacy

Indocin IV may cause problems when taken with other nonsteroidal anti-inflammatory drugs (NSAIDs) or with angiotensin-converting enzyme (ACE) inhibitors. It may also interact with aspirin and drugs related to aspirin, some antibiotics, digoxin, diuretics, drugs that treat blood clots such as warfarin, and steroids such as cortisone. These drug interactions may require an adjustment in the dosage given of Indocin IV, or close monitoring.

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Nonsteroidal Anti-inflammatory Drugs

Nonsteroidal anti-inflammatory drugs, such as ibuprofen and naproxen, are used to reduce inflammation from such conditions as arthritis, back pain or tendinitis. Available over-the-counter, NSAIDs are one of the most common type of medications.

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