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How does ketorolac interact with other substances?

Ketorolac can interact with a number of other medications: angiotensin converting enzyme (ACE) inhibitors, methotrexate, diuretics and pentoxifylline may increase its effect on the kidneys. Selective serotonin reuptake inhibitors (SSRIs) increase the chances of gastrointestinal bleeding. Psychoactive drugs may cause hallucinations. Ketorolac may increase the chances of having a seizure for people who take antiepileptic drugs. Care should be taken when administering the drug along with other nonsteroidal anti-inflammatory drugs (NSAIDs) or with lithium. Interactions may also exist with major tranquilizers and with probenecid.

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Important: This content reflects information from various individuals and organizations and may offer alternative or opposing points of view. It should not be used for medical advice, diagnosis or treatment. As always, you should consult with your healthcare provider about your specific health needs.