How does Aleve (naproxen) interact with other medications and food?

Stacy Wiegman, PharmD

Pharmacy

Aleve may interact with other medications, supplements, and other substances. Do not use Aleve with other medications unless your doctor recommends you do so. Tell your doctor about all medications and supplements you are taking, and be sure to include the following:

ACE inhibitor
antidepressants
antacids
aspirin
beta blockers
blood thinners
diabetes medications
diuretics
ibuprofen
lithium
methotrexate
naproxen
NSAIDs
phenytoin
probenecid
steroids
sulfa antibiotics
sucralfate

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Important: This content reflects information from various individuals and organizations and may offer alternative or opposing points of view. It should not be used for medical advice, diagnosis or treatment. As always, you should consult with your healthcare provider about your specific health needs.

Nonsteroidal Anti-inflammatory Drugs

Nonsteroidal anti-inflammatory drugs, such as ibuprofen and naproxen, are used to reduce inflammation from such conditions as arthritis, back pain or tendinitis. Available over-the-counter, NSAIDs are one of the most common type of medications.

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