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What should I know about Treximet before taking it?

Treximet tablets, active ingredients sumatriptan and naproxen sodium, are prescribed to treat migraine headache pain. You should discuss with your doctor if this medication is appropriate for you. Naproxen is a non-steroidal anti-inflammatory drug (NSAID), which can cause serious health problems in some people.

Do not take Treximet if you have ever had any reaction to its ingredients or to aspirin or any other NSAID. Treximet is not meant to prevent a migraine or for treatment of basilar or hemiplegic migraines. Do not take more than two tablets in 24 hours, and wait at least two hours between doses. Talk to your doctor about any other medications you're taking, because Treximet can interact with many other drugs, including anti-depressants. You should not use Treximet if you are currently taking certain anti-depressant medications including monoamine oxidase inhibitors (MAOI) or selective serotonin reuptake inhibitors (SSRI). Women who are in the last trimester of pregnancy or breastfeeding should not use Treximet.

Let your doctor know before using Treximet if you have heart, kidney or liver disease, diabetes, history of stroke or other clotting problem, fluid retention, any blood disorders, high blood pressure, a blood vessel disease or condition or gastrointestinal conditions. If you smoke, are overweight, in poor health, are past menopause, are over 40, on a low-sodium diet or have a history of alcohol abuse or dependency, tell your doctor as well. This drug has the risk of causing serious heart problems, stomach ulcers or bleeding, a possibly fatal condition called serotonin syndrome, kidney problems and dizziness. Talk to your doctor about these risks.

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Important: This content reflects information from various individuals and organizations and may offer alternative or opposing points of view. It should not be used for medical advice, diagnosis or treatment. As always, you should consult with your healthcare provider about your specific health needs.