What should I know about ibuprofen lysine injections?

An ibuprofen lysine injection is an intravenous nonsteroidal anti-inflammatory medication used to treat patent ductus arteriosus (PDA). PDA affects infants. Ibuprofen lysine injections cause the ductus arteriosus vein to constrict. These constrictions work to close the vein. The ductus arteriosus vein normally closes before birth. If your baby has certain medical conditions in addition to PDA, ibuprofen lysine injection use may not be possible.

Tell your doctor if your baby has any of the following health disorders:

  • bacterial infection, bleeding in the brain, bleeding in the intestines, blood clotting problems, 
  • congenital heart disease, hyperbilirubinemia, inflammation in the intestines (necrotizing enterocolitis), or a viral infection.

If you notice any unusual side effects such as bruising, inflammation at the injection site, fever, or abnormal behavior, talk to your child's doctor right away. Although some side effects are common and expected, others can be more severe and require immediate medical attention.

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Important: This content reflects information from various individuals and organizations and may offer alternative or opposing points of view. It should not be used for medical advice, diagnosis or treatment. As always, you should consult with your healthcare provider about your specific health needs.