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How is stage 4 non-Hodgkin lymphoma diagnosed?

The number and location of tumors developing in the body determines a diagnosis of stage 4 non-Hodgkin lymphoma. This diagnosis process is called staging and involves tests of one or more of the following: a bone marrow biopsy, CT scan, MRI, ultrasound, spinal tap, or PET scan. Stage 4 indicates tumors spread throughout the lymphatic system, as well as invading other tissues, organs, and even the blood stream and bone marrow. It can also be classified as "indolent" in medical terms-meaning the disease is very responsive to treatment and those diagnosed with it can expect to survive many years-or aggressive, requiring intensive treatment. It should be noted that stage 4 non-Hodgkin lymphoma is almost always diagnosed as indolent.

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