Why might my grandmother have bone loss from taking Symbicort?

Long-term use of Symbicort, which contains a steroid, can lead to bone loss. Your grandmother’s risk for bone loss is higher if the condition runs in your family. Her chance of getting bone loss is also increased if she smokes cigarettes, does not exercise or does not get enough vitamin D and calcium in her diet. Her doctor may order a bone density test to see if she has bone loss.