What is propylhexedrine used for?

Dr. Michael Roizen, MD
Internal Medicine

Propylhexedrine (brand name Benzedrex) is a drug that is categorized as a topical nasal decongestant. Translating that into layman’s English, this drug is taken usually with an inhaler to help a stuffy nose clear up. So if you’ve got a cold, allergies, hay fever, or even sinusitis, propylhexedrine may help relieve your congestion.


However, it is important to note that this medication can have some serious interactions with certain antidepressants and other medications, so talk to your doctor to make sure it’s an acceptable choice for you.

Propylhexedrine relieves nasal congestion. You may want to use this drug if you have allergies or a cold. Propylhexedrine is a vasoconstrictor. This means that the medicine narrows the blood vessels. When inhaled, propylhexedrine slows down the blood flow to the passages inside your nose. To take this medication, spray it into your nostrils. Follow the directions on the package. If you use this medication as directed but your symptoms persist after three days, talk to your doctor.

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Important: This content reflects information from various individuals and organizations and may offer alternative or opposing points of view. It should not be used for medical advice, diagnosis or treatment. As always, you should consult with your healthcare provider about your specific health needs.