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Are there side effects to over-the-counter antihistamines?

Dr. Mehmet Oz, MD
Cardiology (Cardiovascular Disease)
Drowsiness is the most common side effect of over-the-counter antihistamines. Use caution if you need to operate machinery or stay alert for other reasons. Antihistamines work by countering the action of histamine, a substance your body releases when you're having an allergic reaction. Some non-prescription antihistamines are formulated to be non-sedating. Talk to your doctor about the best options for you.

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Important: This content reflects information from various individuals and organizations and may offer alternative or opposing points of view. It should not be used for medical advice, diagnosis or treatment. As always, you should consult with your healthcare provider about your specific health needs.