Are there any risks in taking diphenhydramine?

There are generally no serious risks in taking diphenhydramine. However, in rare cases, allergic reactions to diphenhydramine have occurred. Symptoms of this include: hives, rash, closing of the throat and swelling of the face, lips or tongue. Also, certain medications should not be taken with diphenhydramine. These include monoamine oxidase inhibitors (MAOIs), such as phenelzine. Lower doses of diphenhydramine may be required for people with asthma, hyperthyroidism, stomach ulcers, enlarged prostate, hypertension or glaucoma. This medication may cause side effects in a breastfeeding baby; do not breastfeed while taking diphenhydramine.  

Continue Learning about Nasal Agent

What is cromolyn nasal spray?
Donna Hill Howes, RNDonna Hill Howes, RN
Cromolyn nasal spray (NasalCrom) reduces allergy symptoms by preventing cells in the air passages fr...
More Answers
What should I know before taking a decongestant?
Donna Hill Howes, RNDonna Hill Howes, RN
If you have an enlarged prostate, decongestants may prevent you from completely emptying your bladde...
More Answers
Is there an alternate medicine to Doxylamin and diphenhydramine?
Doxylamine and diphenhydramine are both H-1 antagonists, which mean they are both antihistamines in ...
More Answers
How do antihistamines relieve allergy and sinus symptoms?
Sigma NursingSigma Nursing
Antihistamines block histamines, which are chemicals responsible for many allergy symptoms. Antihist...
More Answers

Important: This content reflects information from various individuals and organizations and may offer alternative or opposing points of view. It should not be used for medical advice, diagnosis or treatment. As always, you should consult with your healthcare provider about your specific health needs.