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Can antihistamines prevent orgasm?

Some over the counter antihistamines, such as diphenhydramine, can cause erectile dysfunction and therefore lead to problems with orgasm. Other newer antihistamines such as loratidine, fexofenadine, and certrizine do not have these same side effects.

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Important: This content reflects information from various individuals and organizations and may offer alternative or opposing points of view. It should not be used for medical advice, diagnosis or treatment. As always, you should consult with your healthcare provider about your specific health needs.