Though its exact causes are unknown, there are several factors that may increase the risk of rhabdomyosarcoma. The risk of rhabdomyosarcoma may be increased if a child has certain inherited genetic conditions. Some of these conditions include Li-Fraumeni syndrome, neurofibromatosis, Costello syndrome, Noonan syndrome, and Beckwith-Wiedemann syndrome. These inherited conditions are pretty rare, but children who are affected have a higher risk of developing rhabdomyosarcoma. Other than these genetic conditions, researchers have not really identified any other factors that may increase a child's risk of this type of cancer.
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