Who should not take Flexeril?

You should not take the muscle relaxant Flexeril (cyclobenzaprine) if:
  • you are allergic to any of its ingredients -- you take antidepressant drugs known as monoamine oxidase inhibitors (MAOIs), such as phenelzine or tranylcypromine, or if you have taken an MAOI within the past 14 days
  • you have an overactive thyroid gland, moderate to severe liver problems or heart problems (such as an irregular heartbeat or congestive heart failure, or conduction problems) 
  • you have recently had a heart attack

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Important: This content reflects information from various individuals and organizations and may offer alternative or opposing points of view. It should not be used for medical advice, diagnosis or treatment. As always, you should consult with your healthcare provider about your specific health needs.