Who should not take naproxen/esomeprazole delayed-release tablets?

Tell your doctor if you or any relative has ever had any factors that could raise your risk of suffering complications from naproxen/esomeprazole delayed-release tablets. Risk factors include: asthma, smoking, drinking more than three alcoholic drinks a day, polyps in your nose, dehydration, poorly controlled diabetes, and heart disease or circulation problems, such as heart failure or leg edema or high blood pressure. Other risk factors include: kidney disease, liver disease, stomach bleeding or ulcers or an unusual or allergic reaction to naproxen, aspirin, other NSAIDs, other medicines, foods, dyes or preservatives.

Naproxen/esomeprazole delayed-release tablets may raise your risk of having a stroke or heart attack. Naproxen may also cause ulcers, bleeding, or holes in your stomach or intestines. The longer you take naproxen, the greater your risk of complications. Heavy drinkers, older people and those with heart disease, are at greater risk of complications.

Taking these drugs shortly before or after coronary artery bypass graft surgery may cause complications. Your doctor will perform blood tests and other procedures to check how these drugs are affecting your body.

Before taking naproxen/esomeprazole delayed-release tablets, tell your doctor if you take any medications that may interact adversely.

Women who are breastfeeding should not take this medication. The drug should only be used in pregnancy if the benefits clearly outweigh the potential risks. Animal studies have suggested the drug may have harmful effects on a fetus, but there are no good human studies.

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Important: This content reflects information from various individuals and organizations and may offer alternative or opposing points of view. It should not be used for medical advice, diagnosis or treatment. As always, you should consult with your healthcare provider about your specific health needs.